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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd57e4cebde09ddbf0132aa5beb122650662871d40f87a0d27f7b6e8976b99462' 
  AND token = 'CcHWPeg9+tj6ey3+Yexmc9RCWaYVLM0uMFtTORZLA9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}