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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfc859f4dde0e82436a94028731247b62ef80e6d5d369c4309fb188e83aba97c' 
  AND token = 'EmpEoW5DBoDEOtgbQDTpwr3KRSwtr3PKA/BY3noW0Vc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}