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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d844a36286c5ae02236f5c1c4e2be94e1e16e54b5beb62a08e9159adbf1df4d' 
  AND token = 'UrJKo9V480lM39r1tmcbjTeBg3U8pQEDI5cB2SDyFQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}