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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c327cbf7cfa1494c93b78c20aaf7376f36841fed94bf205af10a5349b4cfe67' 
  AND token = 'XhIKW8FpaT3FIJY37P3XZULFqk7DQMuT/++xYK28l9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}