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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a0e26558a8bbfede37e8eaf81fc55968d6d722052f44f020371671b6420be09' 
  AND token = 'aThvdkOUnILqtEbHTwuHCHQbQpXUzH6ecisX8FpkrUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}