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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '188462d3f8f208e92e1de1f63e6550f07268c982f79e9b30d2faa8c80859ac46' 
  AND token = 'a6/5bdmjzdkq39LAoQhWRXY35pt7kgwtUGFJxWd8+iM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}