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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a8daca4aa3b76fc13c12e8497c7191f2e9ed4e7453b8c66779faa207717744c' 
  AND token = '24ww3tx87kdh4z1a/zVIA0eNXB0tgJzafkrJujfPTi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}