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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e073f001423100be6ce73d31f7668fe837bb48dc3753e00317817372b934a09' 
  AND token = '7QjFPbOsWv3x2Eq7X3hvBt1iy+DyQCaJP9OobHVEd+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}