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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '224f53809f276545f6cc36390b2954e3b6c609d130099850bbb6b9264db00be1' 
  AND token = 'gKH8+lhkSBbi9lWjuqIiMWgy6y1tMLGv5WWGAEiR7po=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}