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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '072c7187a3823e778979617131b79da21b4b085c8399805daa40b46d27ef7122' 
  AND token = '3sZvytk3wdcIGvvWj2TR69oRobt53+iLhwTWkZNF9Tc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}