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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25f326ed5516b29e00abc35fd5841439d23feda94bde385c4dcb46f3ad644428' 
  AND token = 'v4UsojpOKvm9SupxpqCZXOtMWgFo5j7it5p5F3FP40w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}