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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb643242dba955449e4843f4f1e75f82a9d6aefb0004f04dc578b824dd24aba6' 
  AND token = 'HeWOm1iZeO2Eu7xBeumzq8HRmjAJiGqSLnaK9Jx8RNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}