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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2067da3a79fbb9a4a08497e63734f5bbccd1ba7313266fdfdde32ef646c442df' 
  AND token = 'MlkDn7+Wlkjym6U/stVqqOAxEY7eq2RQZyDP+07cAZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}