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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64a80eddab623ea0198baf42c59eec48b70308769618c5159f0fefc37d652da0' 
  AND token = 'FB87UiywJL2uCcLVfqw12KXfC5yDs/7teqBSk9XuKug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}