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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af8471370570bbf36bfa52e4749b5b17a55dac893137ff0b9b3d0ea30dfe6724' 
  AND token = 'GrmFuw4MSQYr3E47ysBZkQlt7dg7hwsSO5vRShU2dZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}