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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7c8162fbc0af3d034297488d5af73cebc03c403ed87a29f28057ff044c95bf8' 
  AND token = 'vI6hsIMQlNBprIFGOZ/cl0UEed3X4FPXu9uj9dR9Zhc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}