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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed1aef2a964d82eaac6add8d877894007f25612d993ebf385fe084c36da9ed85' 
  AND token = 'P/0Hfm4eNEp8lTwiC8sx6MODGLx4C4RBwjObAT4gtiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}