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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a22a96c816e46bf3f2c5fca447fbc415572148ed1e512d82e606479a5b998c25' 
  AND token = '+eF5afaOZToSMVpG75b9Y7/PNTp/RA6k4nI6qTIiyNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}