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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4553866ca93e5210a7b3f709e7a5d86da631a97d3415eb6c0be570d7ea598327' 
  AND token = 'ybWq9hckG1MBccRsoShxXYYCau5wqK2cxiV6Il2Qz00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}