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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be20a8f3a694507b1ca689a621a7ecd4504b6e200012ef95d1ecdfb0590537ad' 
  AND token = 'oDtu/WD5hJJvJkkSq80RNHqB3JTMgBrAWzVgUzMsDiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}