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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e04d420686846f9c8db67714fb7fb6fb76456ddfc0f24adaaa26765c45c2580e' 
  AND token = 'Ec7MHbHkDiiUhzzNBS2y2RI208ALDmhfboy1oxdEBQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}