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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a2144ff5392f2f05af9781b7c1b32e02b9245cf9a330dbc558696692623754c' 
  AND token = 'oYf8vo2oKYQdDuBThTS286ElwmORxyuiczbyaIOkIeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}