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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c81b2bbe601541c3998b91970fd95b0e7a81604ff8d4e0ddc4da907f3b8aa0a' 
  AND token = '3+OrWg4X/gDQPOSZZ3DAZe6Wdz564ZXrahE3Var+65I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}