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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3ddd5853e9793289db9f6124aac8d950069dcaa5d39120b7b58e75ce470cf48' 
  AND token = '49uZUubG+rx6z66UlSpspE8gZOafsKaAt8a3KunyLu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}