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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64f4f408caf0e5172d8489704108bd4aeb0162bc6cbe98531a90c1c0b4671613' 
  AND token = 'iTzvFYSXdAgTp2yOKbcp8fmfzQFwU3gjcQof5ILEixw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}