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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2a0806296b2c8253f690dbee557a8f3375695bee39d0d420af876ee25e3df22' 
  AND token = '86EAgJVx8B7Empo7dyUW24NInP4LZTHCMdpAj9QaCSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}