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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '745a44a0387e4dee850a0a75e45b666db7e0c1bb7c28c70ebc31ca89fc29bd82' 
  AND token = 'yQ5a42WBjWen4aAxC46DrM+khOBkgHXPsGY+X/Ijeho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}