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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fd3cd48a9a4394cca80e4fcd4f55801c53b2e80face97795fadf9685c8b22c6' 
  AND token = '/QdBpuOLZC1Jk/9mNBZSJWHEEGnXcckIhVl+ERSzAZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}