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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b553c39195da1665cd25366535f614e934426c4feb9e9c8a8d2db9ed3313dccd' 
  AND token = 'F/AkMaJM27INiaHX7b9F16iMIL7t8X5ZqtGo4G+r/PE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}