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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed5202a3f4028090b75c59115ed9764347e02fe7a5e34c64d95558df2f18aad5' 
  AND token = 'F5IIHse69G72aRT61MJxxw6holKuJWZzD51WVXBfHzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}