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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '335d79e6d729a915294fc4cdc7e702254aca050878418a46691b95f069d7a7fa' 
  AND token = '1TM5YdDG2GyEXmxi6kSE9k+kDxelnQMJUDxrPOhHLS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}