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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e40100d1d93dea597f4b141d2b0a66ab53df181a94cf6caa76c679b0fecbb32d' 
  AND token = 'xq1kpIgSUlSCcz+lzkKRqAr9PpSKEiz2C7RmUJLT2t8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}