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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01e5f1fcb2c6c2b473200538a16dd5925ad6c3ac7335f7a4e710cb19ed61fd5f' 
  AND token = 'V+UQ+TbFCxtiHvY1a409+KdPT72xhpFasKFy0nsNNTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}