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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efb2241ea15adc9f13d1ef506c741fb54f79f835621bc8ecfc8dc08ad127d52b' 
  AND token = 'dVmI3A+Kk+zM/YVPMhWSKrSSaxKK9ZsGPARoxC4CNEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}