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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '118a59dbc784030eecced557d09989a91149c5c21af55c3b5ee122abd7b7fc69' 
  AND token = '6l+ehpGmVcCWWQen4UmrePJZrItCVm9KF7RLNJLnlaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}