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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '140623ad6829218c338d10ce06db35549d8e2b4f88d3f7aab7eb014f8ac22050' 
  AND token = '4Z1s0NH7sklc6u0oGbLcEH0tAPnJq/RlFc9xd9fkDkE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}