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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8769267c71512ece031b42e382ac5994f32c4ec58d4f66b11b8cc9e4fb10c0a0' 
  AND token = 'NqTLaDFWeW2nUfTP597lfBOi63oB9sIaDcycNUHVL3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}