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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '150da7adb59d7d8e2a9f5f7a9a40ea9742079f35d5b9668b9dd154239c3fc0be' 
  AND token = 'qU/KeziyRcYaV+o50SBJQsKuR4FAeftip+fEpKM/RS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}