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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f94785349bc889843e4626ad86cd88f4ffa1878cfa965c591d78797f2f4d7c34' 
  AND token = '/XaVuM2h4nFWX733pjrV3xcrV64aWS8l/GWqxWM/GxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}