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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5005fe0a966e78f5d0b30c417bf4a9803525a82c0813700422d5321209c73211' 
  AND token = '604QTLGSjoku0C4dedzObgn6W6m6vf1WTrUqfAwsabk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}