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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9bb0b372436456d5226d1bcc9d8f03875898d56024c001d20170c0126ed9886' 
  AND token = 'kMIf8oRqFpLM+ATHuwX+M8vNLkC0H/r8UTW3yyaz3cI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}