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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eac81b2991354a663891866a8c493a188a32aeb041a07b2aa54eaa5b9543716' 
  AND token = '2LlwZLr7tRYFaV4Y24MlrCuOrMETDuCgqGKGKhDHYRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}