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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6600a9df4602a7e0f0e80ff72b0c631bbb197e8cd1df6b65505fc717f22418c' 
  AND token = 'Ee9ejv9mtXTg4GSzYnRHs9MBrf17soJckfK1WLYVkuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}