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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f108190c786a451e54c2c046c665bd6d83d360ce36ebf0398b65e76f9bc587f' 
  AND token = 'kUFujyVEDo6EYgOPZ0cGBaUoIutNQbIYyhLKY9qPqZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}