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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15f3fc13a3de698643afea299806313cfb74f2a5a43bac3963d28367f65f826e' 
  AND token = 'F4uNQLfIn5daKrj6NIW33fW4+9jZTPuFzfrAdMcvbRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}