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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16dc4a7dc711732ee5b70a8ca596f6c949ec4a8769cb4090a6ac60b5bb8b1168' 
  AND token = 'ceUNIaQPMnvNn0u9YGhoezUWdWVrzQQBq4ynUe6XXBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}