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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8746c62f6d731b6fa4fa8b9dc606b33262c0911952e54e5f84311b6f4768a764' 
  AND token = 'HzAiiG7EkC0ttH9sLJTmZKCct+DMorO1EvpTxCTZoX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}