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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '976d663f2bf8140cf33d19bc8f9df3c27c63978a3abbc0e3164b629816b5b80d' 
  AND token = 'H04AVi4CzLrLdHsMDlEWfPn0eB6FJoNL8UQkrbCW/zw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}