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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59ae7b597fe7acc7c6025c1ad138162d9f9910851fabadcbbeb52c3da965d003' 
  AND token = 'ofIq1LbJDyqejDz0665fO0f+wBaYQOvZqBPZrTlvev8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}