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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4922fb453e95b5c9c97293811f1865f7afdda76a985fbb76c4d40fb988993789' 
  AND token = '48G6LxynuNNBmZHUns8x3NamibpUJycb4P0RWUVLYkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}